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Article

Diseases of complement dysregulation-an overview.

Seminars in immunopathology - 1 Jan 2018

Wong Edwin K S, Kavanagh David

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy (C3G), and paroxysmal nocturnal hemoglobinuria (PNH) are prototypical disorders of complement dysregulation. Although complement overactivation is common to all, cell surface alternative pathway dysregulation (aHUS), fluid phase alternative pathway dysregulation (C3G), or terminal pathway dysregulation (PNH) predominates resulting in the very different...

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Source

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Identifiers

PMID: 29327071
DOI: 10.1007/s00281-017-0663-8
PMCID: PMC5794843

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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