Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.

The Journal of clinical investigation - 1 May 2015

McCracken Melissa N, Vatakis Dimitrios N, Dixit Dhaval, McLaughlin Jami, Zack Jerome A, Witte Owen N

Abstract excerpt

Adoptive transfer of tumor-reactive T cells can successfully reduce tumor burden; however, in rare cases, lethal on-target/off-tumor effects have been reported. A noninvasive method to track engineered cells with high sensitivity and resolution would allow observation of correct cell homing and/or identification of dangerous off-target locations in preclinical and clinical applications. Human deoxycytidine kinase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HLA-A2 Antigen
Share to Chemotaxis, Leukocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytotoxicity Tests, Immunologic

Share to Genes, Synthetic

Share to Graft Survival

Share to Immunotherapy, Adoptive

Share to Lentivirus

Share to Melanoma, Experimental

Source

Open in PubMed Open full text

Identifiers

PMID: 25822024
DOI: 10.1172/JCI77326
PMCID: PMC4463193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.PMID 25822024Read ↗

Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene.Semantic proximity Read ↗

Visualizing cell–cell communication using synthetic notch activated MRISemantic proximity Read ↗

Intratumoral B7H3:CD3 Bispecific T-cell Engager Drives Localized T-cell Accumulation in Canine Sarcoma PatientsSemantic proximity Read ↗

Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biologySemantic proximity Read ↗

Specific Imaging of CD8+ T-Cell Dynamics with a Nanobody Radiotracer against Human CD8βSemantic proximity Read ↗

In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift.Semantic proximity Read ↗

Enhanced AkaLuc Bioluminescence Imaging for Longitudinal Intravital Monitoring of Minimal Residual Disease in a Murine Model of Triple-negative Breast CancerSemantic proximity Read ↗

A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodiesSemantic proximity Read ↗

A dual-luciferase bioluminescence system for the assessment of cellular therapiesSemantic proximity Read ↗

Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter systemSemantic proximity Read ↗

Radioimmunoscintigraphy of human met-expressing tumor xenografts using met3, a new monoclonal antibody.Semantic proximity Read ↗

Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.