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Article

Ordering Practices and Utilization of a Next-Generation Sequencing Panel for Myeloproliferative Neoplasms.

The journal of applied laboratory medicine - 5 May 2026

Cooke Tyler, Soderquist Craig R, Mansukhani Mahesh M, Hsiao Susan J

Abstract excerpt

BACKGROUND: JAK2, CALR, and MPL mutations are defining features of myeloproliferative neoplasms (MPNs). Molecular testing for variants in these genes is standard of care in the diagnosis of MPNs. A high reimbursement denial rate led to review of ordering practices and test utilization to identify potential areas for optimization, education, or triage to improve laboratory stewardship. METHODS: MPN panel orders...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41499245
DOI: 10.1093/jalm/jfaf197

Genes

CALR
JAK2
MPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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