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Article

The molecular management of classic myeloproliferative neoplasm.

Journal of the Egyptian National Cancer Institute - 10 Nov 2025

Soro Charlène G S, Benchikh Sara, Hamouchi Adil El, Morjane Imane, Saile Rachid, Lebrazi Halima, Nassereddine Sanaa

Abstract excerpt

BACKGROUND: Whole-genome sequencing has enabled the development of a wide range of analytical tools to search for abnormalities associated with tumors. As classic myeloproliferative neoplasms (MPNs) are associated with genomic alterations in hematopoietic stem cells, the World Health Organization (WHO) recommendations include since 2008 molecular investigations as an important part of the diagnosis and management...

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PMID: 41212396
DOI: 10.1186/s43046-025-00325-8
PMCID: PMC13313426

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