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Article

Structural framework to address variant-gene relationship in primary open-angle glaucoma.

Vision research - 1 Jan 2025

Singh Nivedita, Kizhatil Krishnakumar, Duraikannu Durairaj, Choquet Hélène, Saidas Nair K

Abstract excerpt

Primary open-angle glaucoma (POAG) is a complex, multifactorial disease leading to progressive optic neuropathy and irreversible vision loss. Genome-Wide Association Studies (GWAS) have significantly advanced our understanding of the genetic loci associated with POAG. Expanding on these findings, Exome-Wide Association Studies (ExWAS) refine the genetic landscape by identifying rare coding variants with potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 39520803
DOI: 10.1016/j.visres.2024.108505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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