Article

A large deletion spanning multiple enhancers near <i>PITX2</i> increases primary open-angle glaucoma risk

2026-03-02

Abstract excerpt

<h4>Importance</h4> Genome-wide association studies have identified hundreds of common single nucleotide polymorphisms (SNPs) and small insertions/deletions (indels) associated with primary open-angle glaucoma (POAG) risk, though these variants have modest effect sizes and individually may have minor contributions to disease development. As whole-genome sequencing data is becoming more readily available, structur...

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Literature Corpus work: 42f9a03b-20df-5f22-b9fc-4640eb3d7580
DOI: 10.64898/2026.02.26.25342774

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