Article
Identification of regulatory genes associated with POAG by integrating expression and sequencing data.
Ophthalmic genetics - 1 Feb 2025
Wang Xizi, Zhang Qiang, Zhao Dongdong, Li Xiaofen, Yi Lili, Li Siyuan, Wang Xin, Gu Mingliang, Gao Jianlu, Jia Xiaodong
Abstract excerpt
BACKGROUND: Primary open-angle glaucoma (POAG) is a subtype of glaucoma that accounts for 60%~70% of all cases. Its pathogenic mechanism is intricate and its pathogenic process is concealed. Numerous significant biological processes associated with POAG continue to be elucidated. METHODS: In this study, by exploring the expression data of POAG tissues and normal tissues, we mined the regulatory lncRNAs and mRNAs...
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