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Article

Protein-RNA interaction dynamics reveal key regulators of oncogenic KRAS-driven cancers.

Scientific reports - 7 Nov 2024

Ban Ka-Yun, Na Yong-Woo, Song Juhan, Kim Jong-Seo, Kim Jimi

Abstract excerpt

KRAS is one of the most frequently mutated oncogenes across various cancers. Oncogenic KRAS mutations rewire cellular signaling, leading to significant alterations in gene expression. RNA-binding proteins (RBPs) play a pivotal role in gene expression regulation by post-transcriptionally controlling various aspects of RNA metabolism. It has become clear that interactions between RBPs and RNA are frequently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39511334
DOI: 10.1038/s41598-024-78333-2
PMCID: PMC11544019

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