Article
Some, but not all, retromer components promote morphogenesis of C. elegans sensory compartments.
Developmental biology - 1 Feb 2012
Oikonomou Grigorios, Perens Elliot A, Lu Yun, Shaham Shai
Abstract excerpt
The endings of sensory receptor cells often lie within specialized compartments formed by glial cells. The main sensory organ of Caenorhabditis elegans, the amphid, provides a powerful setting for studying glial compartment morphogenesis. Our previous studies showed that amphid compartment size is controlled by opposing activities of the Nemo-like kinase LIT-1, which promotes compartment expansion, and the...
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