Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mineralocorticoid receptor antagonism attenuates arteriovenous fistula stenosis by modulating the phenotype of vascular smooth muscle cells.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 30 May 2025

Liu Yamin, Chen Bohan, Chen Kai, Wang Yufei, Zhou Chunyu, Liang Xianhui, Wang Kai, Wang Pei

Abstract excerpt

BACKGROUND: Fistula stenosis is a primary contributor to arteriovenous fistula (AVF) failure in maintenance hemodialysis patients. Emerging data indicated excessive fibrotic remodeling was the primarily contributor to fistula stenosis during AVF remodeling. The mineralocorticoid receptor (MR) has been implicated in vascular remodeling across various cardiovascular pathologies. However, its role in AVF remodeling,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Constriction, Pathologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Rats, Sprague-Dawley

Share to Receptors, Mineralocorticoid

Share to Renal Dialysis

Source

Open in PubMed Open full text

Identifiers

PMID: 39510964
DOI: 10.1093/ndt/gfae247
PMCID: PMC12123322

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mineralocorticoid receptor antagonism attenuates arteriovenous fistula stenosis by modulating the phenotype of vascular smooth muscle cells.PMID 39510964Read ↗

CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation.Semantic proximity Read ↗

Mineralocorticoid Receptor/Rac1-Driven Podocyte Injury in Fabry Disease: Finerenone and Spironolactone migitate the overactive signaling cascadeSemantic proximity Read ↗

LncRNA-LncDACH1 mediated phenotypic switching of smooth muscle cells during neointimal hyperplasia in male arteriovenous fistulas.Semantic proximity Read ↗

Cellular phenotypes in human stenotic lesions from haemodialysis vascular access.Semantic proximity Read ↗

Endovascular Biopsy and Endothelial Cell Gene Expression Analysis of Dialysis Arteriovenous Fistulas: A Feasibility Study.Semantic proximity Read ↗

Sulforaphane prevents abdominal aortic aneurysm formation through the inhibition of phenotypic switching of vascular smooth muscle cells and inflammation via the activation of Nrf2.Semantic proximity Read ↗

A New Role for the Aldosterone/Mineralocorticoid Receptor Pathway in the Development of Mitral Valve Prolapse.Semantic proximity Read ↗

Venous stenosis in a pig arteriovenous fistula model--anatomy, mechanisms and cellular phenotypes.Semantic proximity Read ↗

Uremic serum exposure leads to differential phenotypic switch in porcine arterial and venous smooth muscle cells.Semantic proximity Read ↗

Uremia modulates the phenotype of aortic smooth muscle cells.Semantic proximity Read ↗

The Single Cell Landscape of the Human Vein After Arteriovenous Fistula Creation and Implications for Maturation FailureSemantic proximity Read ↗

Adipose phenotype predicts early human autogenous arteriovenous hemodialysis remodeling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.