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Article

Causal associations between the insulin-like growth factor family and sarcopenia: a bidirectional Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Liu Jili, Chen Meng, Xia Xin, Wang Zhaolin, Wang Yanqin, Xi Ling

Abstract excerpt

Objective: Insulin-like growth factor (IGF) is closely associated with sarcopenia, yet the causal relationship of this association remains unclear. This study aims to explore the potential causal relationship between members of the IGF family and sarcopenia from a genetic perspective through bidirectional Mendelian randomization (MR) analysis using two-sample datasets. Methods: Five genetically predicted factors...

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Identifiers

PMID: 39507055
DOI: 10.3389/fendo.2024.1422472
PMCID: PMC11537870

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