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Article

A bi-directional Mendelian randomization study of sarcopenia-related traits and type 2 diabetes mellitus.

Frontiers in endocrinology - 1 Jan 2023

Chen Simin, Yan Shikang, Aiheti Nuerbiyamu, Kuribanjiang Kaidiriyan, Yao Xuemei, Wang Qian, Zhou Tao, Yang Lei

Abstract excerpt

Background: Previous studies have reported an association between sarcopenia and type 2 diabetes mellitus (T2DM), but causation was prone to confounding factors. A more robust research approach is urgently required to investigate the causal relationship between sarcopenia and T2DM. Methods: The bi-directional two-sample MR study was carried out in two stages: Sarcopenia-related traits were investigated as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36967750
DOI: 10.3389/fendo.2023.1109800
PMCID: PMC10031051

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