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Article

Interplay of Acquired Risk Factors, Age, and Genetic Predisposition in Incident Stroke: A Prospective Cohort Study.

Journal of the American Heart Association - 15 Jul 2025

Wu Yu-Biao, Huang Ze-Gui, He Wan-Bing, You Si, Zhang Shao-Ling, Cai Yang-Wei, Meng Yuan-Li, Gao Qing-Yuan, Wang Jing-Feng, Zhang Hai-Feng, Gao Jing-Wei, Liu Pin-Ming

Abstract excerpt

BACKGROUND: Stroke is the leading cause of disability and death worldwide, and its pathogenesis involves various risk factors. This study aimed to investigate the associations between acquired risk factors, age, and genetic predisposition in the incidence of stroke. METHODS AND RESULTS: We analyzed 404 873 participants (age, mean±SD, 56.46±8.10 years; 45.97% men) from the UK Biobank cohort, all without a history...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40611497
DOI: 10.1161/JAHA.125.040962
PMCID: PMC12533630

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