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Article

Causal relationship between cortical structural changes and onset of anxiety disorder: evidence from Mendelian randomization.

Cerebral cortex (New York, N.Y. : 1991) - 5 Nov 2024

Teng Fei, Wang Mengqi, Lu Zhangyu, Zhang Chunyu, Xiao Linglong, Chen ZhaoMing, Huang Mengshuang, Xie Linglin, Chen Zheyu, Wang Wei

Abstract excerpt

Previous studies have reported a correlation between anxiety disorders and changes in brain structure, yet the specific alterations in brain region volumes remain unclear. This study aimed to infer the causal relationship between anxiety disorders and changes in brain structure volume through Mendelian Randomization analysis. We selected 63 cortical structure volumes from the GWAS database as exposure data and...

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Anxiety Disorders
Atrophy
Cerebral Cortex
Genome-Wide Association Study
Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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PMID: 39503246
DOI: 10.1093/cercor/bhae440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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