Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Topical Platelet Exosomes Reduce Senescence Signaling in Human Skin: An Exploratory Prospective Trial

4 Oct 2024

Abstract excerpt

BACKGROUND: Cellular senescence, an irreversible cell cycle arrest with secretory phenotype, is a hallmark of skin aging. Regenerative exosome-based approaches, such as topical human platelet extract (HPE), are emerging to target age-related skin dysfunction. OBJECTIVE: To evaluate the cellular and molecular effects of topical HPE for skin rejuvenation after 12 weeks of twice daily use. METHODS: Skin biopsies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Skin Protection and Aging
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39480039
DOI: 10.1097/dss.0000000000004426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Topical Platelet Exosomes Reduce Senescence Signaling in Human Skin: An Exploratory Prospective TrialPMID 39480039Read ↗

The role of cellular senescence in skin aging and age-related skin pathologiesSemantic proximity Read ↗

Unveiling senescence-associated secretory phenotype in epidermal aging: insights from reversibly immortalized keratinocytesSemantic proximity Read ↗

Reduction of senescence-associated secretory phenotype and exosome-shuttled miRNAs by Haritaki fruit extract in senescent dermal fibroblasts.Semantic proximity Read ↗

Cellular Senescence in Human Skin Aging: Leveraging SenotherapeuticsSemantic proximity Read ↗

Targeting Dermal Fibroblast Senescence: From Cellular Plasticity to Anti-Aging TherapiesSemantic proximity Read ↗

The impact of cellular senescence in skin ageing: A notion of mosaic and therapeutic strategies.Semantic proximity Read ↗

Skin senescence—from basic research to clinical practiceSemantic proximity Read ↗

Effect of Blood-Derived Products on Senescence Associated Se-Cretory Phenotype in an Etoposide Induced Senescence Human Dermal Fibroblast ModelSemantic proximity Read ↗

Senomorphic Activity of a Novel Standardized Propolis Extract in Human Dermal Fibroblasts: Molecular Insights into Clinically Proven Anti-Wrinkle EfficacySemantic proximity Read ↗

Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin modelsSemantic proximity Read ↗

Mapping epidermal and dermal cellular senescence in human skin agingSemantic proximity Read ↗

Epigenetic Regulation of Skin Cells in Natural Aging and Premature Aging DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.