Article

Effect of Blood-Derived Products on Senescence Associated Se-Cretory Phenotype in an Etoposide Induced Senescence Human Dermal Fibroblast Model

2023-12-06

Abstract excerpt

Blood-derived products (BP) like citrate-platelet-rich plasma (CPRP) or hyperacute serum (HAS) are known to contain many growth factors. Combined mitogenic and DNA damaging stimuli might lead to increased senescent cell burden and altered senescence-associated secretory pheno-type (SASP). Therefore, the senescent state was extensively tested by γH2AX staining, p21 Q-PCR and western blot, growth curves and senescen...

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Literature Corpus work: cb8d10f5-a030-5d08-ac44-84363a0b51f2
DOI: 10.20944/preprints202312.0304.v1

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