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APOL1 Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans

26 Oct 2024

Abstract excerpt

Background Apolipoprotein L1 gene ( APOL1 ) variants are risk factors for chronic kidney disease (CKD) among Black Americans. Data are sparse on the genetic epidemiology of CKD and the clinical association of APOL1 variants with CKD in West Africans, a major group in the Black population. Methods We conducted a case–control study involving participants from Ghana and Nigeria who had CKD stages 2 through 5,...

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PMID: 39465900
DOI: 10.1056/nejmoa2404211

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