Article
APOL1 kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Kidney international - 1 Nov 2025
Ojo Akinlolu O, Adu Dwomoa, Bramham Kate, Freedman Barry I, Gbadegesin Rasheed A, Ilori Titilayo O, Jefferson Nichole, Olabisi Opeyemi A, Susztak Katalin, Young Bessie A, Cheung Michael, King Jennifer M, Grams Morgan E, Jadoul Michel, Ulasi Ifeoma I
Abstract excerpt
In people of African ancestry, apolipoprotein L1 gene (APOL1) variants have been identified as causing increased risk of progressive chronic kidney disease (CKD). In April of 2024, Kidney Disease: Improving Global Outcomes (KDIGO) convened a Controversies Conference on APOL1 Kidney Disease in Accra, Ghana. The goals of the conference were to review and discuss current evidence and controversies on APOL1 kidney...
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