Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerin preserves stem cell survival through maintenance of centrosome and nuclear lamina structure.

Development (Cambridge, England) - 15 Nov 2024

Jones Samuel D, Miller Jack E B, Amos Madilynn M, Hernández Julianna M, Piaszynski Katherine M, Geyer Pamela K

Abstract excerpt

Drosophila female germline stem cells (GSCs) complete asymmetric mitosis in the presence of an intact, but permeable, nuclear envelope and nuclear lamina (NL). This asymmetric division requires a modified centrosome cycle, wherein mitotic centrosomes with mature pericentriolar material (PCM) embed in the NL and interphase centrosomes with reduced PCM leave the NL. This centrosome cycle requires Emerin, an NL...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Survival
Share to Centrosome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Germ Cells

Share to Interphase

Share to Mitosis

Share to Nuclear Lamina

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 39465887
DOI: 10.1242/dev.204219
PMCID: PMC11586520

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerin preserves stem cell survival through maintenance of centrosome and nuclear lamina structure.PMID 39465887Read ↗

Nuclear lamina dysfunction triggers a germline stem cell checkpoint.Semantic proximity Read ↗

Drosophila male and female germline stem cell niches require the nuclear lamina protein Otefin.Semantic proximity Read ↗

The functional significance of centrosomes in mammalian meiosis, fertilization, development, nuclear transfer, and stem cell differentiationSemantic proximity Read ↗

Mitotic errors drive rapid clearance of polyploidy during intestinal regeneration despite robust centrosome clusteringSemantic proximity Read ↗

The yeast polo kinase Cdc5 regulates the shape of the mitotic nucleus.Semantic proximity Read ↗

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes.Semantic proximity Read ↗

Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis.Semantic proximity Read ↗

Centrosomes Split in the Presence of Impaired DNA Integrity during MitosisSemantic proximity Read ↗

The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in<i>Drosophila</i>Semantic proximity Read ↗

The Drosophila nuclear lamina protein otefin is required for germline stem cell survival.Semantic proximity Read ↗

Discovery of Alstrom syndrome gene as a regulator of centrosome duplication in asymmetrically dividing stem cells in Drosophila.: Supplementary table-mass spectrometrySemantic proximity Read ↗

Endosome-generated interior actin network regulates mitotic fidelity and organelle homeostasis downstream of P-cadherinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.