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Fusion of breast cancer MCF-7 cells with mesenchymal stem cells rearranges interallelic gene expression and enhances cancer malignancy.

Biochemical and biophysical research communications - 3 Dec 2024

Mawaribuchi Shuuji, Iida Maiko, Haramoto Yoshikazu

Abstract excerpt

Fusion among normal cells is tightly regulated and required for the developmental processes of an organism. Cancer cell fusion appears relatively rare but is associated with generating new hybrid cancer cells with aggressive properties. However, it remains unclear how cancer cells acquire aggressiveness via cell fusion. Here, we report changes in cell proliferative capacity, cell motility, anticancer drug...

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Identifiers

PMID: 39461012
DOI: 10.1016/j.bbrc.2024.150887

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