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Article

Altered Tumor Plasticity after Different Cancer Cell Fusions with MSC

6 Nov 2020

Abstract excerpt

While cell fusion demonstrates an important pathway during tissue development and regeneration of distinct organs, this process can also contribute to pathophysiological phenotypes during tumor progression. Hybrid cell formation after heterofusion between cancer cells and various other cell types within the tumor microenvironment is observed in vitro and in vivo. In particular, mesenchymal stroma/stem-like cells...

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PMID: 33172211
DOI: 10.3390/ijms21218347

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