Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC)

5 Jan 2018

Abstract excerpt

BACKGROUND: Fusion of breast cancer cells with tumor-associated populations of the microenvironment including mesenchymal stroma/stem-like cells (MSC) represents a rare event in cell communication whereby the metastatic capacity of those hybrid cells remains unclear. METHODS: Functional changes were investigated in vitro and in vivo following spontaneous fusion and hybrid cell formation between primary human MSC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Mesenchymal stem cell research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29329589
DOI: 10.1186/s12964-018-0215-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC)PMID 29329589Read ↗

Spontaneous formation of tumorigenic hybrids between breast cancer and multipotent stromal cells is a source of tumor heterogeneity.Semantic proximity Read ↗

Altered Tumor Plasticity after Different Cancer Cell Fusions with MSCSemantic proximity Read ↗

Spontaneous fusion of MSC with breast cancer cells can generate tumor dormancySemantic proximity Read ↗

Cell Fusion of Mesenchymal Stem/Stromal Cells and Breast Cancer Cells Leads to the Formation of Hybrid Cells Exhibiting Diverse and Individual (Stem Cell) CharacteristicsSemantic proximity Read ↗

Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cellsSemantic proximity Read ↗

Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells.Semantic proximity Read ↗

Cancer Cell Fusion and Post-Hybrid Selection Process (PHSP)Semantic proximity Read ↗

MSC stimulate ovarian tumor growth during intercellular communication but reduce tumorigenicity after fusion with ovarian cancer cellsSemantic proximity Read ↗

Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variantsSemantic proximity Read ↗

Spontaneous Fusion of MSC with Breast Cancer Cells Can Generate Tumor DormancySemantic proximity Read ↗

Extracellular Events Involved in Cancer Cell–Cell FusionSemantic proximity Read ↗

Hybrid Formation and Fusion of Cancer Cells In Vitro and In VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.