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Article

Oncogenic transformation of normal breast epithelial cells co-cultured with cancer cells

18 Aug 2018

Abstract excerpt

The heterogeneity in human breast cancer poses a challenge for effective treatment. Better understanding of tumor initiation and development will help to resolve this problem. Current models explaining intratumoral diversity include cancer stem cells, clonal evolution and cancer cell dedifferentiation and reprogramming. Herein, a new model, cancer transmission, is proposed to explain cancer heterogeneity. We...

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PMID: 30160604
DOI: 10.1080/15384101.2018.1511510

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