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Article

Genetic susceptibility to caffeine intake and metabolism: a systematic review.

Journal of translational medicine - 22 Oct 2024

Low Jazreel Ju-Li, Tan Brendan Jen-Wei, Yi Ling-Xiao, Zhou Zhi-Dong, Tan Eng-King

Abstract excerpt

BACKGROUND: Coffee and tea consumption account for most caffeine intake and 2-3 billion cups are taken daily around the world. Caffeine dependence is a widespread but under recognized problem. OBJECTIVES: To conduct a systematic review on the genetic susceptibility factors affecting caffeine metabolism and caffeine reward and their association with caffeine intake. METHODOLOGY: We conducted PubMed and Embase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39438936
DOI: 10.1186/s12967-024-05737-z
PMCID: PMC11515775

Genes

ABCG2
ADORA2A
AHR
ALDH2
BDNF
CYP1A2
CYP2A6
DRD2
GCKR
HECTD4
MLXIPL
PDSS2
POR
SLC6A4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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