Article
Coffee, caffeine-related genes, and Parkinson's disease: a case-control study.
Movement disorders : official journal of the Movement Disorder Society - 30 Oct 2008
Facheris Maurizio F, Schneider Nicole K, Lesnick Timothy G, de Andrade Mariza, Cunningham Julie M, Rocca Walter A, Maraganore Demetrius M
Abstract excerpt
An inverse association between coffee and Parkinson's disease (PD) has been reported. However, it remains uncertain why some but not all coffee drinkers are less susceptible to PD. We considered the possibility of a pharmacogenetic effect. In our study, we included 1,208 subjects (446 case-unaffected sibling pairs and 158 case-unrelated control pairs) recruited from an ongoing study of the molecular epidemiology...
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