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Article

A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor.

Sleep - 1 Jul 2012

Byrne Enda M, Johnson Julie, McRae Allan F, Nyholt Dale R, Medland Sarah E, Gehrman Philip R, Heath Andrew C, Madden Pamela A F, Montgomery Grant W, Chenevix-Trench Georgia, Martin Nicholas G

Abstract excerpt

OBJECTIVES: To identify common genetic variants that predispose to caffeine-induced insomnia and to test whether genes whose expression changes in the presence of caffeine are enriched for association with caffeine-induced insomnia. DESIGN: A hypothesis-free, genome-wide association study. SETTING: Community-based sample of Australian twins from the Australian Twin Registry. PARTICIPANTS: After removal of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Adenosine A2A

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Source

Open in PubMed Open full text

Identifiers

PMID: 22754043
DOI: 10.5665/sleep.1962
PMCID: PMC3369232

Genes

GBP4
PRIMA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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