Article
Discovery and characterization of temperature adaptation modules by mining L-glutamate decarboxylase derived from psychrophilic microorganisms.
International journal of biological macromolecules - 1 Dec 2024
Song Chenshuo, Luo Jie, Qiao Jun, Liu Zhongmei, Cheng Zhongyi, Wang Qiong, Zhou Zhemin, Han Laichuang
Abstract excerpt
Directed alterations of the enzyme's temperature adaptations, such as thermostability and optimal catalytic temperature (Topt), are usually the way to go in order to meet the applications, however they are limited by the understanding between protein structure and function. Glutamate decarboxylase (GADs) is a common enzyme in the food industry. In this study, we identified and characterized three novel...
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