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Article

Different modifications by vanillin in cytotoxicity and genetic changes induced by EMS and H2O2 in cultured Chinese hamster cells.

Mutation research - 1 Aug 1992

Tamai K, Tezuka H, Kuroda Y

Abstract excerpt

The modifying effects of vanillin on the cytotoxicity and 6-thioguanine (6TG)-resistant mutations induced by two different types of chemical mutagens, ethyl methanesulfonate (EMS) and hydrogen peroxide (H2O2), were examined using cultured Chinese hamster V79 cells. The effects of vanillin on H2O2-induced chromosome aberrations were also examined. Vanillin had a dose-dependent enhancing effect on EMS-induced...

Topics

Animals
Benzaldehydes
Cells, Cultured
Chi-Square Distribution
Chromosome Aberrations
Cricetinae
Cricetulus
DNA Repair
Ethyl Methanesulfonate
Flavoring Agents
Hydrogen Peroxide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mutagenesis

Mutagenicity Tests

Mutation

Thioguanine

Source

Identifiers

PMID: 1379329
DOI: 10.1016/0027-5107(92)90229-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1379329-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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