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Article

Serotonin transporter 5-HTTLPR polymorphism and escitalopram treatment response in patients with major depressive disorder.

BMC psychiatry - 15 Oct 2024

Jarčušková Dominika, Tkáč Ivan, Hlaváčová Nataša, Yaluri Alena Stančáková, Kozárová Miriam, Habalová Viera, Klimčáková Lucia, Židzik Jozef, Javorský Martin, Bednářová Aneta

Abstract excerpt

BACKGROUND: There is no doubt that genetic factors have the potential to predict the therapeutic outcomes of antidepressants in patients with major depressive disorder (MDD). This study investigated the association between genetic variants involved in serotonin signaling and brain-derived neurotrophic factor (BDNF) with the response to escitalopram treatment in patients with MDD. We focused on examining the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP2C19

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Share to Receptor, Serotonin, 5-HT2A

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Identifiers

PMID: 39407134
DOI: 10.1186/s12888-024-06162-8
PMCID: PMC11481807

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