Association between functional polymorphisms in serotonin transporter gene (SLC6A4) and escitalopram treatment response in depressive patients in a South Indian population.

doi:10.1007/s00228-020-02866-4

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Article

Association between functional polymorphisms in serotonin transporter gene (SLC6A4) and escitalopram treatment response in depressive patients in a South Indian population.

European journal of clinical pharmacology - 1 Jun 2020

Mandal Tatiyana, Bairy Laxminarayana Kurady, Sharma Podila Satya Venkata Narasimha

Abstract excerpt

PURPOSE: Ethnicity plays a key role in deciding the direction of the association between serotonin transporter gene polymorphisms and treatment response of selective serotonin reuptake inhibitors (SSRIs). The present study explored the association of 5HTTLPR and 5HTTLPR-rs25531 polymorphisms with the treatment response of escitalopram in South Indian patients with major depressive disorder. METHODS: A total of...

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PMID: 32253447
DOI: 10.1007/s00228-020-02866-4

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