Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression.

doi:10.1016/j.euroneuro.2009.01.010

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Article

Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jun 2009

Maron Eduard, Tammiste Anu, Kallassalu Kristi, Eller Triin, Vasar Veiko, Nutt David J, Metspalu Andres

Abstract excerpt

Several studies and meta-analyses have implicated a polymorphism in the promoter region of the serotonin transporter (5-HTT) gene, 5-HTTLPR in treatment outcomes of selective serotonin re-uptake inhibitors in patients with major depression. In this study we investigated the impact of 5-HTTLPR and a functional SNP rs25531 on the treatment outcomes to escitalopram in depressive patients. The study sample consisted...

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PMID: 19272758
DOI: 10.1016/j.euroneuro.2009.01.010

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