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pK205R targets the proximal element of IFN-I signaling pathway to assist African swine fever virus to escape host innate immunity at the early stage of infection

15 Oct 2024

Abstract excerpt

African swine fever virus (ASFV) is a nuclear cytoplasmic large DNA virus (NCLDV) that causes devastating hemorrhagic diseases in domestic pigs and wild boars, seriously threatening the development of the global pig industry. IFN-I plays an important role in the body's antiviral response. Similar to other DNA viruses, ASFV has evolved a variety of immune escape strategies to antagonize IFN-I signaling and...

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PMID: 39405340
DOI: 10.1371/journal.ppat.1012613

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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