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African swine fever virus pH240R enhances viral replication via inhibition of the type I IFN signaling pathway

14 Feb 2024

Abstract excerpt

African swine fever (ASF) is an acute, hemorrhagic, and severe infectious disease caused by ASF virus (ASFV) infection. At present, there are still no safe and effective drugs and vaccines to prevent ASF. Mining the important proteins encoded by ASFV that affect the virulence and replication of ASFV is the key to developing effective vaccines and drugs. In this study, ASFV pH240R, a capsid protein of ASFV, was...

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PMID: 38353534
DOI: 10.1128/jvi.01834-23

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