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ASFV infection induces macrophage necroptosis and releases proinflammatory cytokine by ZBP1-RIPK3-MLKL necrosome activation

17 Jun 2024

Abstract excerpt

African swine fever (ASF) is an infectious disease characterized by hemorrhagic fever, which is highly pathogenic and causes severe mortality in domestic pigs. It is caused by the African swine fever virus (ASFV). ASFV is a large DNA virus and primarily infects porcine monocyte macrophages. The interaction between ASFV and host macrophages is the major reason for gross pathological lesions caused by ASFV....

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PMID: 38952452
DOI: 10.3389/fmicb.2024.1419615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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