Article

Multiomic Analyses Direct Hypotheses for Creutzfeldt-Jakob Disease Risk Genes

2024-07-21

Abstract excerpt

Prions are assemblies of misfolded prion protein that cause several fatal and transmissible neurodegenerative diseases, with the most common phenotype in humans being sporadic Creutzfeldt-Jakob disease (sCJD). Aside from variation of the prion protein itself, molecular risk factors are not well understood. Prion and prion-like mechanisms are thought to underpin common neurodegenerative disorders meaning that the e...

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Literature Corpus work: 3616e1ea-92dc-5e6b-8fb4-70cdd82d6dc8
DOI: 10.1101/2024.07.19.24310476

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