Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatial and Single‐Cell Transcriptomics Reveals the Regional Division of the Spatial Structure of MASH Fibrosis

14 Oct 2024

Abstract excerpt

OBJECTIVE: To elucidate the regional distribution of metabolic dysfunction-associated steatohepatitis (MASH) fibrosis within the liver and to identify potential therapeutic targets for MASH fibrosis. METHODS: Liver sections from healthy controls, patients with simple steatosis and MASH patients were analysed using spatial transcriptomics integrated with single-cell RNA-seq. RESULTS: Spatial transcriptomics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Disease Diagnosis and Treatment
Share to Liver physiology and pathology
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39400982
DOI: 10.1111/liv.16125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatial and Single‐Cell Transcriptomics Reveals the Regional Division of the Spatial Structure of MASH FibrosisPMID 39400982Read ↗

Spatial Transcriptomic Signature of Progressive Fibrosis in Human MASLD: Role of Senescence and Metabolic ReprogrammingSemantic proximity Read ↗

Single cell multiomics reveals drivers of metabolic dysfunction-associated steatohepatitisSemantic proximity Read ↗

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cellsSemantic proximity Read ↗

Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)Semantic proximity Read ↗

AI-based phenotyping of hepatic fiber morphology to inform molecular alterations in metabolic dysfunction-associated steatotic liver disease.Semantic proximity Read ↗

An Integrated Pipeline for Cell-Type Annotation, Metabolic Profiling, and Spatial Communication Analysis in the Liver using Spatial TranscriptomicsSemantic proximity Read ↗

A spatial map of human liver cirrhosis reveals the patho-architecture and gene signatures associated with cell state transitions during liver diseaseSemantic proximity Read ↗

Spatial single-cell interactome and niche-specific molecular signatures in alcohol-related liver diseaseSemantic proximity Read ↗

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosisSemantic proximity Read ↗

Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolutionSemantic proximity Read ↗

A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liverSemantic proximity Read ↗

Single Cell Transcriptomics Reveal Genomic Indicators of Nonalcoholic Fatty Liver DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.