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Advancing Precision Oncology: Whole-Exome Sequencing in Endometrial Cancer Liquid-Based Cytology.

Archives of pathology & laboratory medicine - 1 Jun 2025

Takamatsu Reika, Nakamura Kohei, Chiyoda Tatsuyuki, Tsuji Kosuke, Kawano Ryutaro, Yoshimi Naoki, Yamagami Wataru, Nishihara Hiroshi

Abstract excerpt

CONTEXT.—: Diagnostic strategies for endometrial cancer have been evolving, with cytologic analysis being considered a key method in integrated oncologic diagnostics because of its less invasive nature and adaptability to various assessments. Liquid-based cytology (LBC) has emerged as a promising method for intact DNA preservation; it exhibits improved efficiency in advanced sequencing applications such as...

Topics

Humans
Female
Endometrial Neoplasms
Exome Sequencing
Precision Medicine
Mutation
Middle Aged
Aged
Microsatellite Instability
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA Mutational Analysis

Biomarkers, Tumor

Liquid Biopsy

Cytodiagnosis

Source

Identifiers

PMID: 39396820
DOI: 10.5858/arpa.2024-0137-OA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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