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Article

Polymorphic variation of the DEFB1 gene might contribute to the development of ankylosing spondylitis: a preliminary study.

Molecular biology reports - 12 Oct 2024

Fernández-Torres Javier, Zamudio-Cuevas Yessica, Martínez-Flores Karina

Abstract excerpt

BACKGROUND: Ankylosing spondylitis (AS) is an inflammatory disease that affects the spine and can cause peripheral arthritis, enthesitis, and dactylitis, as well as extra-articular manifestations such as uveitis and inflammatory bowel disease. β-Defensins are antimicrobial peptides involved in the activation and regulation of several immune cell types that may influence the inflammatory response in AS. The aim...

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PMID: 39395079
DOI: 10.1007/s11033-024-09985-6

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