Article
A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis.
Genes and immunity - 1 Jan 2010
Schaefer A S, Richter G M, Nothnagel M, Laine M L, Rühling A, Schäfer C, Cordes N, Noack B, Folwaczny M, Glas J, Dörfer C, Dommisch H, Groessner-Schreiber B, Jepsen S, Loos B G, Schreiber S
Abstract excerpt
Periodontal diseases are complex inflammatory diseases and affect up to 20% of the worldwide population. An unbalanced reaction of the immune system toward microbial pathogens is considered as the key factor in the development of periodontitis. Defensins have a strong antimicrobial function and are important contributors of the immune system toward maintaining health. Here, we present the first systematic...
Topics
Join the communities discussing this publication.