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Article

Association of IL-1A and IL-1B polymorphisms with ankylosing spondylitis among the Chinese Han population: a case-control study.

Oncotarget - 25 Apr 2017

Li Lei, Shi Baolan, Zheng Wenkai, Xing Wenhua, Zhao Yan, Li Feng, Xin Daqi, Jin Tianbo, Zhu Yong, Yang Xuejun

Abstract excerpt

Ankylosing spondylitis (AS) is a complex and chronic inflammatory disease with a high heritage. Previous study has shown that IL-1A and IL-1B involved in inflammatory reaction. But little is known about single nucleotide polymorphisms (SNPs) of IL-1A and IL-1B associated with AS. We conducted a case-control study among 267 AS cases and 297 healthy controls from China. In the genetic model analysis, we found the...

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Identifiers

PMID: 28423679
DOI: 10.18632/oncotarget.16004
PMCID: PMC5438649

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