Article
Association of β-defensin gene copy number variations with ankylosing spondylitis in Chinese population: A case-control study.
Modern rheumatology - 1 Jan 2016
Ding Ning, Yang Xiao, Zhang Li, Cai Guoqi, Xia Qing, Fan Dazhi, Li Xiaona, Hu Yanting, Liu Li, Xin Lihong, Wang Li, Xu Shengqian, Xu Jianhua, Zou Yanfeng, Ding Changhai, Pan Faming
Abstract excerpt
OBJECTIVES: To explore the association of β-defensin gene copy number variations (CNVs) with ankylosing spondylitis (AS). METHODS: In this study, 405 unrelated Chinese Han patients with AS and 401 unrelated healthy controls were enrolled. The copy numbers of DEFB4 gene (2 fragments) were measured by AccuCopy™ methods. The association of DEFB4 gene CNVs with AS susceptibility was analyzed by chi-square and...
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