Association study of polymorphisms rs4552569 and rs17095830 and the risk of ankylosing spondylitis in a Taiwanese population.

doi:10.1371/journal.pone.0052801

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Article

Association study of polymorphisms rs4552569 and rs17095830 and the risk of ankylosing spondylitis in a Taiwanese population.

PloS one - 1 Jan 2013

Wei James Cheng-Chung, Hsu Yu-Wen, Hung Kuo-Sheng, Wong Ruey-Hong, Huang Chun-Huang, Liu Yi-Tzu, Guo Yuh-Cherng, Ikegawa Shiro, Chang Wei-Chiao

Abstract excerpt

Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints. However, the development of anklosing spondylitis is unclear. Human leukocyte antigens HLA-B27 and ERAP1 have been widely reported to be associated with AS susceptibility. A recent genome-wide association study (GWAS) showed that two new susceptibility loci between EDIL3 and HAPLN1 at 5q14.3 (rs4552569)...

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Identifiers

PMID: 23308121
DOI: 10.1371/journal.pone.0052801
PMCID: PMC3537770

Genes

ANO6
EDIL3
ERAP1
HAPLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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