Article
Association Study of IL-12B Polymorphisms Susceptibility with Ankylosing Spondylitis in Mainland Han Population.
PloS one - 1 Jan 2015
Zhang Li, Fan Dazhi, Liu Li, Yang Ting, Ding Ning, Hu Yanting, Cai Guoqi, Wang Li, Xin Lihong, Xia Qing, Li Xiaona, Xu Shengqian, Xu Jianhua, Yang Xiao, Zou Yanfeng, Pan Faming
Abstract excerpt
OBJECTIVE: This study aims to determine whether the genetic polymorphisms of IL-12B gene is a susceptibility factor to Ankylosing spondylitis (AS) in mainland Han Chinese population. METHOD: Eight single-nucleotide polymorphisms (SNPs) (rs10045431, rs11167764, rs3212227, rs6556412, rs6556416, , and ) in the IL-12B gene were genotyped by iMLDR Assay technology in 400 patients [96%...