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Article

Ladinin-1 in actin arcs of oral squamous cell carcinoma is involved in cell migration and epithelial phenotype.

Scientific reports - 1 Oct 2024

Abé Tatsuya, Yamazaki Manabu, Nozumi Motohiro, Maruyama Satoshi, Takamura Kaori, Ohashi Riuko, Ajioka Yoichi, Tanuma Jun-Ichi

Abstract excerpt

Histopathologically, oral squamous cell carcinoma (OSCC) consists of well-defined interfaces with adjacent non-cancerous epithelium. Previously, we found that SCC tissues expressed higher levels of specific proteins at this interface. Ladinin-1 (LAD1) is one of the specific molecules that has increased expressions in cancer fronts; however, its function in OSCC is unknown. Therefore, this study aimed to elucidate...

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Identifiers

PMID: 39354061
DOI: 10.1038/s41598-024-74041-z
PMCID: PMC11445451

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