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Article

Emerging Roles of Ruk/CIN85 in Vesicle-Mediated Transport, Adhesion, Migration and Malignancy

17 Mar 2010

Abstract excerpt

Ruk/CIN85 is an adaptor protein. Similar to many other proteins of this type, Ruk/CIN85 is known to take part in multiple cellular processes including signal transduction, vesicle-mediated transport, cytoskeleton remodelling, programmed cell death and viral infection. Recent studies have also revealed the potential importance of Ruk/CIN85 in cancer cell invasiveness. In this review we summarize the various roles...

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PMID: 20331533
DOI: 10.1111/j.1600-0854.2010.01061.x

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