Article

Title: LAMC2 promotes oral squamous cell carcinoma growth by activating the p-ERK/c-Myc signaling pathway

2023-11-15

Abstract excerpt

<h4>Purpose: </h4> Oral squamous cell carcinoma (OSCC) is one of the most common types of head and neck carcinoma. Limited therapies are available for OSCC due to lack of molecular therapeutic targets. <h4>Methods: </h4> Bioinformatics analysis, in vitro experiments and animal model studies were performed to elucidate the crucial role and clinical significance of LAMC2 in the progression of OSCC. And we examined t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0236ca87-7e0e-550b-bcbf-ab30ee647152
DOI: 10.21203/rs.3.rs-3595269/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Title: LAMC2 promotes oral squamous cell carcinoma growth by activating the p-ERK/c-Myc signaling pathwayDOI 10.21203/rs.3.rs-3595269/v1Read

Overexpression of Laminin-5 Gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascadeSemantic proximity Read

LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancerSemantic proximity Read

LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer.Semantic proximity Read

Study on the mechanism of KIF2C/PLK1 in the growth and metastasis of oral squamous cell carcinomaSemantic proximity Read

LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer GrowthSemantic proximity Read

FGF8 induces epithelial-mesenchymal transition and promotes metastasis in oral squamous cell carcinomaSemantic proximity Read

Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1Semantic proximity Read

TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2.Semantic proximity Read

BCL11A Promotes the Progression of Laryngeal Squamous Cell CarcinomaSemantic proximity Read

ANLN promotes carcinogenesis in oral cancer by regulating PI3K/mTOR signaling pathwaySemantic proximity Read

HIF-1α-mediated LAMC1 expression is an unfavorable predictor of prognosis for glioma patients: Evidence from pan-cancer analysis and validation experimentsSemantic proximity Read

HIF-1α-mediated LAMC1 overexpression is an unfavorable predictor of prognosis for glioma patients: evidence from pan-cancer analysis and validation experimentsSemantic proximity Read