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Article

Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis.

The Journal of pathology - 1 Jul 2011

Lai Ming-Tsung, Hua Chun-Hung, Tsai Ming-Hsui, Wan Lei, Lin Ying-Ju, Chen Chih-Mei, Chiu I-Wen, Chan Carmen, Tsai Fuu-Jen, Jinn-Chyuan Sheu Jim

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is highly invasive and is associated with frequent tumour recurrences and lymph node metastases. Identification of genes involved in the aggressiveness of OSCC may provide new targets for clinical intervention. A genome-wide study based on the Sty1 250K SNP array indicated the involvement of the Talin-1 (TLN1) gene in the 9p13.3 amplicon, which was further validated by dual...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21547905
DOI: 10.1002/path.2867

Genes

TLN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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