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Characterisation of the HLA-DQ alpha eplet 52SK targeting the DQA1*01 alleles family.

HLA - 1 Oct 2024

Devriese Magali, Lee Jar How, Meng Tina, Nong Thoa, Shih Neng Jen Remi, Lemonnier François A, Miyadera Hiroko, Giraldo Lisa, Usureau Cédric, Toutirais Olivier, Lowe Dave, Taupin Jean Luc

Abstract excerpt

Eplet 52SK is unique in the HLA eplet registry as targeting the whole family of DQA1*01 alleles. It is proposed as an antibody-verified eplet but has not been validated enough to deserve this label. Especially, confusion can occur with reactivity targeting the 52PQ eplet which is present on the DQB1*05 and DQB1*06 alleles families, as DQ molecule stability imposes DQA1*01 to selectively associate with these DQ-β...

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Alleles
Histocompatibility Testing
HLA-DQ alpha-Chains
HLA-DQ Antigens
Isoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39352216
DOI: 10.1111/tan.15700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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