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Article

Standard Single Antigen HLA Luminex Panels Predict Most, but Not All, Antibody Reactivity Against Alleles in Extended Panels.

HLA - 1 Jul 2026

Chu Gerard J, Cassar Rachel L, Guthrie Petrina, Taverniti Anne, Quach David, Goddard Louise, Kelly Shane, Gutierrez Federico, Sullivan Lucy C, Carroll Robert P

Abstract excerpt

Current Luminex platforms cannot represent the totality of polymorphism in human HLA. Although supplemental, extended panels are available, they are not universally applied and their diagnostic value is uncertain. It is unclear whether standard bead kits can accurately predict the reactivity seen in extended panels. This study investigated, when using the standard panel alone, whether a closest related bead...

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Alleles
Histocompatibility Testing
HLA Antigens
Isoantibodies
Microspheres

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PMID: 42454409
DOI: 10.1111/tan.70797
PMCID: PMC13370519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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