Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DQ Barrier

3 Jan 2013

Abstract excerpt

BACKGROUND: The United Network for Organ Sharing algorithm for deceased-donor kidney allocation considers only the human leukocyte antigen (HLA)-A, HLA-B, and HLA-DR loci. Although HLA-DQ serologic specificities can be entered as unacceptable antigens, they are assigned only by the identity of the DQβ chain, disregarding the role of the similarly polymorphic α chain. DQα/β combinations result in unique antigenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Organ Donation and Transplantation
Share to Renal Diseases and Glomerulopathies
Share to Renal Transplantation Outcomes and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23288109
DOI: 10.1097/tp.0b013e318277b30b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DQ BarrierPMID 23288109Read ↗

The complexity of human leukocyte antigen (HLA)-DQ antibodies and its effect on virtual crossmatching.Semantic proximity Read ↗

Determination of unacceptable HLA antigen mismatches in kidney transplant recipients.Semantic proximity Read ↗

HLA-DQ barrier: effects on cPRA calculations.Semantic proximity Read ↗

Incidence and impact of allele-specific anti-HLA antibodies and high-resolution HLA genotyping on assessing immunologic compatibility.Semantic proximity Read ↗

Significance of HLA-DQ in kidney transplantation: time to reevaluate human leukocyte antigen–matching priorities to improve transplant outcomes? An expert review and recommendationsSemantic proximity Read ↗

Hiding in plain sight: Misinterpretation of immunogenic DPB epitopes within G/P groups.Semantic proximity Read ↗

De Novo DQ Donor-Specific Antibodies Are Associated With a Significant Risk of Antibody-Mediated Rejection and Transplant GlomerulopathySemantic proximity Read ↗

Guidelines From the French‐Speaking Society of Histocompatibility and Immunogenetics for Virtual Crossmatching for Deceased Donor Kidney Transplantation and the Use of Wet Crossmatch in the Decision‐Making ProcessSemantic proximity Read ↗

Qualitative, rather than quantitative, differences between HLA-DQ alleles affect HLA-DQ immunogenicity in organ transplantation.Semantic proximity Read ↗

HLA-DQ Mismatches Lead to More Unacceptable Antigens, Greater Sensitization, and Increased Disparities in Repeat Transplant CandidatesSemantic proximity Read ↗

Root cause analysis of limitations of virtual crossmatch for kidney allocation to highly-sensitized patients.Semantic proximity Read ↗

Determination of unacceptable HLA antigen mismatches in kidney transplant recipients: recommendations of the German Society for ImmunogeneticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.